Other covariates sensed provided everyday supplement D and you may multivitamin complement explore, yearly dental office check out (yearly or otherwise not), tooth-grooming regularity (twice a day or otherwise not), flossing regularity, years and you will gender.
Data were accessed and analyzed at the Research Data Centre (RDC) at the University of Manitoba using SPSS 20 (IBM, Armonk, NY), SAS 9.2 (SAS, Cary, NC), and Stata 13 MP (StataCorp LP, College Station, Tex.). As per RDC restrictions, original sample sizes were suppressed. Bootstrap weights for variance estimation and weighted results are presented with degrees of freedom fixed to 11. Descriptive statistics include means and frequencies with 95% confidence intervals (CI). ? 2 tests were used to determine the unadjusted correlation of each categorical independent variable with GI and LOA. Student t tests were used to determine the unadjusted correlation of each continuous independent variable with GI and LOA. Three multiple logistic regression models for GI and for LOA were developed to determine the adjusted association between 25(OH)D levels and GI and LOA, controlling for potential confounders. Model A used 25(OH)D concentration of < 50 nmol/L, model B used 25(OH)D concentration < 75 nmol/L, and model C used mean 25(OH)D concentration. Variables with a p value of ? 0.075 were included in the multiple logistic regression analysis for GI and LOA, with the exception of plasma vitamin D concentration and known risk factors for periodontal disease, such as smoking. A p value ? 0.05 was significant.
The mean 25(OH)D concentrations (95% CI) in the GI and LOA samples were 90.8 (77.5–104.2) and 85.6 (74.6–97.2) nmol/L, respectively. Although mean 25(OH)D levels were above the thresholds for vitamin D sufficiency, 63% of each sample had concentrations below the 75 nmol/L threshold and 25% of each population had 25(OH)D levels < 50 nmol/L.
Although not, whenever confounding details was in fact regulated for, several logistic regression study of GI (Desk dos) showed that merely plaque and you may sex were rather associated with the GI
Bivariate analysis of GI (Table 1) [Ed. Note: All Tables in this article are available in the PDF version]. showed that several variables were significantly associated with 25(OH)D concentrations below the thresholds for vitamin D sufficiency. Participants with 25(OH)D concentrations < 50 nmol/L and < 75 nmol/L had significantly increased odds of having more GI (odds ratio (OR) 1.63 and 1.44, respectively). Those taking vitamin D supplements had significantly lower odds for GI (OR 0.56), while those with diabetes had increased odds of having moderate to severe GI (OR 1.33). Mean BMI was significantly higher among those with the worst GI. Meanwhile, those who reported frequenting a dental professional ? 1 time a year, brushing their teeth twice daily and flossing daily had significantly lower odds for GI. Increased scores for plaque were associated with increased odds for moderate to severe GI. Males had increased odds for GI compared with females, while those in higher-income categories had lower odds for GI than those in lower-income categories.
Girls had down odds of reasonable so you can really serious GI, when you’re large thinking towards plaque directory increased the chances from average so you can really serious GI. Zero tall family relations anywhere between twenty five(OH)D and you may GI is seen in habits A, B or C throughout the multiple logistic regression study out of GI.
Numerous details had been extreme in the bivariate investigation off LOA (Table 3). Contrary to popular belief, getting a beneficial multivitamin otherwise a vitamin D supplement was of increased odds of much more serious LOA. Higher suggest HbA1c values was basically of the increased odds of much more serious LOA just like the is actually HbA1c > 7%. Older age are with the improved likelihood of much more serious LOA, when you’re a living of > $60 000 are regarding the straight down odds of more severe LOA. Zero significant organization try found between 25(OH)D membership and LOA in the bivariate research.